Timothy B Niewold Selected Research

Interferon Type I

1/2022	High Systemic Type I Interferon Activity Is Associated With Active Class III/IV Lupus Nephritis.
1/2022	Interferon pathway lupus risk alleles modulate risk of death from acute COVID-19.
11/2021	Interferon pathway lupus risk alleles modulate risk of death from acute COVID-19.
1/2021	COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease.
12/2020	Type I interferon in the pathogenesis of systemic lupus erythematosus.
1/2020	Distinct Single Cell Gene Expression in Peripheral Blood Monocytes Correlates With Tumor Necrosis Factor Inhibitor Treatment Response Groups Defined by Type I Interferon in Rheumatoid Arthritis.
10/2019	Type I Interferon Predicts an Alternate Immune System Phenotype in Systemic Lupus Erythematosus.
1/2019	High levels of circulating interferons type I, type II and type III associate with distinct clinical features of active systemic lupus erythematosus.
1/2018	Type I interferon in rheumatic diseases.
1/2018	Associations between type I interferon and antiphospholipid antibody status differ between ancestral backgrounds.

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Timothy B Niewold Research Topics

Disease

65	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2022 - 04/2005
17	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 09/2008
12	Rheumatoid Arthritis 10/2021 - 07/2006
8	Dermatomyositis (Dermatopolymyositis) 01/2021 - 06/2009
7	Sarcoidosis (Schaumann Disease) 04/2014 - 08/2010
6	Inflammation (Inflammations) 10/2013 - 01/2010
3	COVID-19 01/2022 - 01/2021
3	Lupus Nephritis 01/2022 - 11/2013
3	Virus Diseases (Viral Diseases) 01/2022 - 10/2013
3	Rheumatic Diseases (Rheumatism) 01/2020 - 10/2016
3	Nephritis 01/2019 - 12/2010
3	Arthritis (Polyarthritis) 01/2019 - 12/2018
3	Vitamin D Deficiency 01/2017 - 06/2011
3	Infections 01/2015 - 04/2005
3	Lymphopenia (Lymphocytopenia) 01/2013 - 04/2005
2	Myositis (Idiopathic Inflammatory Myopathies) 03/2020 - 01/2018
2	Connective Tissue Diseases (Connective Tissue Disease) 01/2016 - 06/2006
2	Genetic Predisposition to Disease (Genetic Predisposition) 12/2015 - 01/2013
2	Thrombotic Thrombocytopenic Purpura 01/2015 - 06/2006
2	Pulmonary Sarcoidosis 04/2014 - 03/2013
2	Multiple Sclerosis 10/2012 - 02/2012
2	Neonatal Systemic lupus erythematosus 10/2012 - 02/2008
2	Human Influenza (Influenza) 12/2011 - 08/2011
2	malar rash 10/2011 - 04/2005
2	Oral Ulcer (Mouth Ulcer) 10/2011 - 04/2005
2	Granuloma 06/2011 - 12/2010
2	Vasculitis (Vasculitides) 12/2010 - 04/2005
2	Hepatitis C 07/2006 - 04/2005
1	Neoplasms (Cancer) 10/2021
1	Cutaneous Lupus Erythematosus 01/2021
1	Polymyositis 03/2020
1	Hemolytic Anemia 01/2019
1	Idiopathic Pulmonary Fibrosis 12/2018
1	Pain (Aches) 04/2018
1	Systemic Scleroderma (Systemic Sclerosis) 01/2018
1	Purine Nucleoside Phosphorylase Deficiency 12/2017
1	Familial Mediterranean Fever (Periodic Disease) 06/2017
1	Necrosis 10/2016
1	Colonic Neoplasms (Colon Cancer) 03/2016
1	Disease Progression 03/2016
1	Neoplasm Metastasis (Metastasis) 03/2016
1	Colorectal Neoplasms (Colorectal Cancer) 03/2016
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 02/2015

Drug/Important Bio-Agent (IBA)

27	Interferon Type IIBA 01/2022 - 02/2008
19	AutoantibodiesIBA 10/2018 - 02/2008
17	InterferonsIBA 11/2022 - 04/2011
17	CytokinesIBA 04/2019 - 09/2008
13	Interferon-alpha (Interferon Alfa)IBA 01/2020 - 04/2005
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 07/2006
7	Antiviral Agents (Antivirals)IBA 01/2022 - 03/2011
6	Interferon Regulatory FactorsIBA 01/2022 - 08/2008
5	Biomarkers (Surrogate Marker)IBA 11/2021 - 08/2010
5	Biological ProductsIBA 03/2020 - 01/2013
5	AntibodiesIBA 01/2019 - 03/2011
4	AutoantigensIBA 12/2018 - 03/2010
3	Rituximab (Mabthera)FDA Link 03/2020 - 06/2006
3	Toll-Like Receptor 7IBA 01/2020 - 01/2013
3	Tumor Necrosis Factor InhibitorsIBA 01/2020 - 12/2010
3	Nucleic AcidsIBA 01/2018 - 01/2013
3	Vitamin D FDA LinkGeneric 01/2017 - 06/2011
3	hydroxide ionIBA 01/2017 - 09/2011
2	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 01/2022 - 11/2021
2	RNA (Ribonucleic Acid)IBA 10/2018 - 10/2013
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018 - 11/2013
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 10/2013
2	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2018 - 01/2013
2	Antigen-Antibody Complex (Immune Complex)IBA 12/2017 - 02/2015
2	B-Cell Activating FactorIBA 01/2017 - 12/2011
2	thiamine triphosphorate (TTP)IBA 01/2015 - 06/2006
2	Adalimumab (Humira)FDA Link 04/2014 - 12/2010
2	OsteopontinIBA 01/2013 - 01/2011
2	Proteins (Proteins, Gene)FDA Link 01/2013 - 06/2010
2	3' Untranslated Regions (3' UTR)IBA 01/2013 - 01/2011
2	SS-A antibodiesIBA 10/2012 - 04/2005
2	EnzymesIBA 06/2010 - 06/2009
1	Immune Checkpoint InhibitorsIBA 10/2021
1	ProteomeIBA 01/2021
1	Interleukin-16 (Interleukin 16)IBA 01/2021
1	ChemokinesIBA 04/2019
1	anti-dsDNA autoantibodyIBA 01/2019
1	P-2 (P 2)IBA 12/2018
1	acetyl 4-aminosalicylic acidIBA 12/2018
1	CitrullineIBA 12/2018
1	Anti-Citrullinated Protein AntibodiesIBA 12/2018
1	Immunoglobulin D (IgD)IBA 10/2018
1	HypoxanthineIBA 12/2017
1	Adenosine (Adenocard)FDA LinkGeneric 12/2017
1	PyrinIBA 06/2017
1	Vitamin D3 24-HydroxylaseIBA 01/2017
1	AMG623 peptibodyIBA 01/2017
1	Interferon-gamma (Interferon, gamma)IBA 11/2016
1	alanylalanine (Ala-Ala)IBA 03/2016
1	Nuclear Antigens (Extractable Nuclear Antigens)IBA 01/2016
1	Folic Acid (Vitamin M)FDA LinkGeneric 12/2015
1	LeptinIBA 12/2015
1	Methotrexate (Mexate)FDA LinkGeneric 12/2015
1	Pattern Recognition ReceptorsIBA 02/2015
1	sirukumabIBA 10/2014

Therapy/Procedure

11	Therapeutics 01/2018 - 04/2005
2	Precision Medicine 01/2020 - 06/2016